Keywords
DILI
infant
phenobarbital
CYP3A4
infant
phenobarbital
CYP3A4
How to Cite
Pinna, A. P., Locci, G., Furno, M., Fanni, D., Faa, G., & Nurchi, A. M. (2013). DILI (drug induced liver injury) in a 9-month-old infant: a rare case of phenobarbital-induced hepatotoxicity. Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), 2(1), 93-95. https://doi.org/10.7363/020114
Abstract
Phenobarbital is one of the most commonly prescribed antiepileptic drugs in childhood, but it can rarely cause serious adverse effects, such as hepatotoxicity that includes a broad clinical spectrum (from isolate hypertransaminasemia to acute liver failure). We describe a case of DILI in a 9-month-old infant caused by chronic therapy with phenobarbital.
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