Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) https://jpnim.com/index.php/jpnim <p>The <strong>Journal of Pediatric and Neonatal Individualized Medicine (JPNIM)</strong> is a peer-reviewed interdisciplinary journal which provides a forum on new perspectives in pediatric and neonatal medicine. The aim is to discuss and to bring readers up to date on the latest in research and clinical pediatrics and neonatology. Special emphasis is on developmental origin of health and disease or perinatal programming and on the so-called ‘-omic’ sciences. Systems medicine blazes a revolutionary trail from reductionist to holistic medicine, from descriptive medicine to predictive medicine, from an epidemiological perspective to a personalized approach. The journal will be relevance to clinicians and researchers concerned with personalized care for the newborn and child. Also medical humanities will be considered in a tailored way.</p> <p>Article submission (original research, review papers, invited editorials and clinical cases) will be considered in the following fields: fetal medicine, perinatology, neonatology, pediatrics, developmental programming, psychology and medical humanities.</p> en-US <p>© Hygeia Press</p> <p> </p> <h3>Copyright and publishing rights</h3> <p>Regarding copyright, before publication, Authors declare that, in consideration of the action of JPNIM in reviewing and editing their submission, they transfer, assign, or otherwise convey all copyright ownership, including any and all rights incidental thereto, exclusively to the JPNIM Publisher (Hygeia Press di Corridori Marinella).</p> <div> <div> <div> <div> <div> <p>Authors have the opportunity to reuse figures, tables and selected text up to 250 words from their article as finally published, providing that full and accurate credit shall be given to publication in JPNIM and that modifications are noted (otherwise no changes may be made).</p> </div> </div> </div> </div> </div> journal@jpnim.com (JPNIM Staff) journal@jpnim.com (JPNIM Staff) OJS 3.2.1.1 http://blogs.law.harvard.edu/tech/rss 60 Selected Lectures of the Meeting “Environment and Health: Messages from the Future”; Cagliari (Italy); October 26, 2024 https://jpnim.com/index.php/jpnim/article/view/e130209 <p class="p1"><strong>Selected Lectures of the Meeting “Environment and Health: Messages from the Future”; Cagliari (Italy); October 26<sup>th</sup>, 2024</strong></p> <p class="p1">&nbsp;</p> <p class="p1"><span class="s1">The Meeting “Environment and Health: Messages from the Future” is a Satellite Meeting of the 20<sup>th</sup> International Workshop on Neonatology and Pediatrics, Cagliari (Italy), October 23<sup>rd</sup>-26<sup>th</sup>, 2024.</span></p> <p class="p1">&nbsp;</p> <p class="p1"><strong>LECT 1. MATERNAL MILK STEM CELLS: WHICH ROLE IN PERINATAL PROGRAMMING OF ADULT DISEASES? •&nbsp;</strong>G. Faa, G. Pichiri, P. Coni, M. Piras, M. Fraschini, A. Reali, V. Fanos (Cagliari, Italy; Philadelphia, Pennsylvania, USA)</p> <p class="p1"><strong>LECT 2. MICROPLASTICS, ENVIRONMENT AND CHIL­DREN HEALTH • </strong>S. Bernasconi (Parma, Italy)</p> <p class="p1"><strong>LECT 3. ENDOCRINE DISRUPTORS (EDs) AND PERI­NATAL PROGRAMMING • </strong>M.E. Street (Parma, Italy)</p> <p class="p1"><strong>LECT 4. THE LIFE MILCH PROJECT: UPDATES AND PERSPECTIVES • </strong>P. Palanza, V. Fanos, A.M. Papini, S. Perrone, T. Ghi, S. Paterlini, M.M. Brambilla, D. Baccolo, C. Scopa, A. Ardenghi, A.M. Shulhai, C. Caffarelli, F. Nuti, F. Fernandez, C. Sartori, F. Alberghi, B. Righi, M. Fontana, L. Filonzi, C. Petrolini, B. Piccolo, E. Turco, R. Pintus, C. Piras, S. Petza, A. Dessì, F. Nonnis Marzano, S. Angioni, S. Vitale, D. Ponzi, A. Pelosi, M.E. Street (Parma, Cagliari, Florence and Reggio Emilia, Italy)</p> <p class="p1"><strong>LECT 5. POTENTIAL OF TERPINEN-4-OL AS AN AD­DITIVE FOR THE PREVENTION OF BACTERIAL INFECTIONS IN NEONATAL BREASTFEEDING • </strong>D. Romeo (Milan, Italy)</p> <p class="p1"><strong>LECT 6. KANGAROO CARE AND NEW HAND MAN­AGEMENT TECHNIQUES • </strong>M. Melis (Cagliari, Italy)</p> <p class="p1"><strong>LECT 7. POTENTIAL OF ESSENTIAL OILS IN THE MANAGEMENT OF MICROBIAL INFECTIONS • </strong>F. Mondello, M. Di Vito, M.L. Ricci (Rome, Italy)</p> <p class="p1"><strong>LECT 8. AFLATOXIN M1 IN MILK: SITUATION AND ANALYTICAL METHODS • </strong>E. Arletti (Modena, Italy)</p> <p class="p1"><strong>LECT 9. TOXICANTS AND TOXINS • </strong>C. Marzetti (Bologna, Italy)</p> <p class="p1"><strong>LECT 10. ONE HEALTH IN MEDICINE • </strong>A. Colangelo (Trento, Italy)</p> <p class="p1"><strong>LECT 11. EPIGENETIC MODULATION OF INFLAMMATION IN THE AGE OF POLLUTION • </strong>M. Greco, G. Terziani (Rivalta di Torino and Brescia, Italy)</p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130209 Sat, 26 Oct 2024 00:00:00 +0200 Selected Lectures of the Meeting “From the First Thousand Days to Aging: Life is a Continuum. Epigenetics, Artificial Intelligence and Environmental Impact”; Cagliari (Italy); October 25, 2024 https://jpnim.com/index.php/jpnim/article/view/e130211 <p class="p1"><strong>Selected Lectures of the Meeting “From the First Thousand Days to Aging: Life is a Continuum. Epigenetics, Artificial Intelligence and Environmental Impact”; Cagliari (Italy); October 25<sup>th</sup>, 2024</strong></p> <p class="p1">&nbsp;</p> <p class="p1"><span class="s1">The Meeting “From the First Thousand Days to Aging: Life is a Continuum. Epigenetics, Artificial Intelligence and Environmental Impact” is a Satellite Meeting of the 20<sup>th</sup> International Workshop on Neonatology and Pediatrics, Cagliari (Italy), October 23<sup>rd</sup>-26<sup>th</sup>, 2024.</span></p> <p class="p1">&nbsp;</p> <p class="p1"><strong>LECT 1. THE POWER OF EPIGENETICS IN THE FIRST THOUSAND DAYS • </strong>V. Fanos (Cagliari, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 2. EPIGENETICS DETERMINING CHILD DEVELOP</strong></span><strong>MENT AND ADULT HEALTH •&nbsp;</strong>M. Stanton (Lübeck, Germany)</p> <p class="p1"><strong>LECT 3. EPIGENETIC FACTORS INFLUENCING LONGEVITY: A PRELIMINARY STUDY • </strong>B. Pische, A.M. Posadino, P. Maccioccu, V. Tanca, G. Terziani, G. Fenu Pintori (Sassari and Brescia, Italy)</p> <p class="p1"><strong>LECT 4. MITOCHONDRIAL EPIGENETIC APPROACH IN NEURODEVELOPMENTAL IMPAIRMENTS • </strong>M. Greco, G. Terziani, G. Damaschi (Rivalta di Torino and Brescia, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 5. MANAGING LIFE BEFORE, DURING AND AFTER </strong></span><strong>PREGNANCY •&nbsp;</strong>S. Nava (Milan, Italy)</p> <p class="p1"><strong>LECT 6. INTEGRATED CLINICAL APPROACH • </strong>B. Allegrini (Monopoli, Italy)</p> <p class="p1"><strong>LECT 7. EPIGENETIC MODULATION OF INFLAMMATION • </strong>K. Wulhfard (Turin, Italy)</p> <p class="p1"><strong>LECT 8. NUTRACEUTICALS AND PHYSIOLOGICAL OXYGEN MODULATION • </strong>S. Benedetti, F. Palma, B. Nuvoli, R. Galati, G. Fenu Pintori, M. Greco, G. Terziani (Urbino, Rome, Sassari, Rivalta di Torino and Brescia, Italy)</p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130211 Fri, 25 Oct 2024 00:00:00 +0200 Selected Lectures of the Congress of Pediatrics; Cagliari (Italy); October 25, 2024 https://jpnim.com/index.php/jpnim/article/view/e130207 <p class="p1"><strong><span class="s1">Selected Lectures of the Congress of Pediatrics; Cagliari (Italy); October 25, 2024</span></strong></p> <p class="p1"> </p> <p class="p1"><span class="s1">The Congress of Pediatrics is a Satellite Meeting of the 20th International Workshop on Neonatology and Pediatrics, Cagliari (Italy), October 23<sup>rd</sup>-26<sup>th</sup>, 2024.</span></p> <p class="p1"> </p> <p class="p1"><strong>LECT 1. TH2 INFLAMMATION AND INBORN ERRORS OF IMMUNITY (IEI): AN EVER-EXPANDING UNIVERSE. FOCUS ON <em>STAT6</em> GAIN-OF-FUNCTION MUTATIONS • </strong>I. Taietti, R. Castagnoli, A. Licari, G.L. Marseglia (Pavia, Italy)</p> <p class="p1"><strong>LECT 2. ANTIBIOTICS AND PROBIOTICS: WHEN TO USE THEM TOGETHER IN PEDIATRICS • </strong>S. Esposito (Parma, Italy)</p> <p class="p1"><strong>LECT 3. THE LONG-TERM FOLLOW-UP OF PRETERM INFANTS • </strong>M. Agosti (Varese, Italy)</p> <p class="p1"><strong>LECT 4. LOW DOSE MEDICINE AND RECURRENT RESPIRATORY INFECTIONS: A DELPHI CONSENSUS SURVEY • </strong>G. Bona, M. Agosti, A. Arrighi, S. Bernasconi, G. Ciprandi, S. Leonardi, G.L. Marseglia (Novara, Varese, Arezzo, Genoa, Catania, and Pavia, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 5. RATIONAL USE OF NUTRACEUTICALS IN </strong></span><strong>PEDIATRICS • </strong>G. Trapani (Sanremo, Italy)</p> <p class="p1"><span class="s2"><strong>LECT 6. THE PAST, THE PRESENT: WHAT FUTURE FOR </strong></span><strong>PEDIATRICS AND PEDIATRIC SOCIETIES? • </strong>S. Vendemmia, I. Pezone, D. Perri, V. Ferrara, M. Vendemmia (Aversa, Rome and Naples, Italy)</p> <p class="p1"><strong>LECT 7. THE FAMILY PEDIATRICIAN AND THE FUTURE • </strong>A. D’Avino (Naples, Italy)</p> <p class="p1"><strong>LECT 8. ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD): NEWS AND UPDATES • </strong>M. Carotenuto (Caserta, Italy)</p> <p class="p1"><strong>LECT 9. FEVER IN PEDIATRIC PATIENTS: AN EAR-NOSE-THROAT (ENT) PERSPECTIVE • </strong>A. Varricchio, F.P. Brunese, A. Varricchio (Campobasso, Caserta and Milan, Italy)</p> <p class="p1"><strong>LECT 10. THROMBOCYTOPENIA IN CHILDREN • </strong>S. Barella (Cagliari, Italy)</p> <p class="p1"><strong>LECT 11. EXPOSURE TO DIGITAL DEVICES IN CHILDHOOD: A STUDY OF 1,332 CHILDREN AND PREADOLESCENTS • </strong>L. Pisano, O. Al Jamal (Cagliari, Italy)</p> <p class="p1"><strong>LECT 12. PRESENTATION OF THE BOOK “<em>PEDIATRIC ELECTROCARDIOGRAPHY – A SIMPLIFIED APPROACH</em>” • </strong>F. De Luca (Catania, Italy)</p> <p class="p1"><strong>LECT 13. PRESENTATION OF THE BOOK “<em>NUTRACEUTICALS IN CLINICAL PRACTICE: SUPPLEMENTATION AND PREVENTION, A REASONED APPROACH TO HEALTH AND WELLNESS</em>” • </strong>G. Trapani (Sanremo, Italy)</p> <p class="p1"><strong>LECT 14. PRIMARY HYPEROXALURIA TYPE 1 • </strong>V. Manca, G. Masnata (Cagliari, Italy)</p> <p class="p1"><strong>LECT 15. HEREDITARY HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HoFH) • </strong>S. Muntoni, C. Piras, L. Atzori (Cagliari, Italy)</p> <p class="p1"><strong>LECT 16. PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS • </strong>A. Pietrobattista (Rome, Italy)</p> <p class="p1"><span class="s3"><strong>LECT 17. ALFA MANNOSIDOSIS: A CHALLENGING DIAG</strong></span><strong>NOSIS FOR A TREATABLE DISEASE • </strong>M. Balzarini, F. Zanco, C. Sbaffi (Cagliari, Italy)</p> <p class="p1"><span class="s3"><strong>LECT 18. LYSOSOMAL ACID LIPASE (LAL) DEFICIENCY: </strong></span><strong>CLINICAL SPECTRUM, DIFFERENTIAL DIAGNOSIS AND SPECIFIC THERAPY • </strong>V. Casotti (Bergamo, Italy)</p> <p class="p1"><strong>LECT 19. AROMATIC L-AMINO ACID DECARBOXYLASE (AADC) DEFICIENCY • </strong>T. Foiadelli (Pavia, Italy)</p> <p class="p1"><strong>LECT 20. ROLE OF ALKALINE PHOSPHATASE IN THE DIAGNOSIS OF HYPOPHOSHATASIA • </strong>S. Savasta (Cagliari, Italy)</p> <p class="p1"><strong>LECT 21. DONKEY MILK BETWEEN PAST AND FUTURE • </strong>V. Fanos, M. Corridori (Cagliari and Quartu Sant’Elena, Italy)</p> <p class="p1"><strong>LECT 22. THE QUALITY OF DONKEY MILK • </strong>M. Martini (Pisa, Italy)</p> <p class="p1"><strong>LECT 23. DONKEY MILK: A RESOURCE IN PRETERM INFANTS NUTRITION • </strong>E. Bertino, G. Maiocco, L. Cavallarin, M. Giribaldi, S. Deantoni, C. Peila, A. Coscia (Turin and Grugliasco, Italy)</p> <p class="p1"><strong>LECT 24. METABOLOMICS OF DONKEY MILK • </strong>F. Cesare Marincola, V. Fanos (Cagliari, Italy)</p> <p class="p1"><strong>LECT 25. THE VIRTUAL KIDNAPPING OF YOUTH BY SOCIAL MEDIA • </strong>M. Leiner (El Paso, Texas, USA)</p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130207 Fri, 25 Oct 2024 00:00:00 +0200 Selected Lectures of the Balkan Meeting of Neonatology; Cagliari (Italy); October 25, 2024 https://jpnim.com/index.php/jpnim/article/view/e130208 <p class="p1"><strong><span class="s1">Selected Lectures of the Balkan Meeting of Neonatology; Cagliari (Italy); October 25<sup>th</sup>, 2024</span></strong></p> <p class="p1"><span class="s1">The Balkan Meeting of Neonatology is a Satellite Meeting of the 20<sup>th</sup> International Workshop on Neonatology and Pediatrics, Cagliari (Italy), October 23<sup>rd</sup>-26<sup>th</sup>, 2024.</span></p> <p class="p1"> </p> <p class="p1"><span class="s1"><strong>LECT 1. MORTALITY RATE OF PRETERM BABIES BORN IN THE TERTIARY MEDICAL CENTER IN TIRANA </strong></span><strong>AND THE IMPACT OF THE IMPROVEMENT OF THE KNOWLEDGE AND SKILLS OF THE HEALTH STAFF • </strong>A. Hoxha-Qosja (Tirana, Albania)</p> <p class="p1"><strong><span class="s1">LECT 2. </span>THE IMPACT OF EARLY CPAP IN THE DELIVERY ROOM IN PRETERM INFANTS WITH A GESTATIONAL AGE OF 31-36<sup>+6</sup> WEEKS • </strong>M. Meta, A. Hoxha-Qosja (Fier and Tirana, Albania)</p> <p class="p1"><strong><span class="s1">LECT 3. </span>IMPACT OF NEONATAL EARLY-ONSET SEPSIS CALCULATOR IN OUR CLINICAL PRACTICE • </strong>G. Koroveshi-Gora, A. Hoxha-Qosja, S. Damo (Tirana, Albania)</p> <p class="p1"><strong><span class="s1">LECT 4. </span>MATERNAL DIET AND BREASTFEEDING • </strong>S. Deantoni, E. Bertino, C. Peila, S. Gandino, A. Coscia (Turin and Moncalieri, Italy)</p> <p class="p1"><strong><span class="s1">LECT 5. </span>NUTRITION AND GROWTH OF PRETERM BABIES IN NICUs • </strong>E. Hatzidaki (Heraklion, Greece)</p> <p class="p1"><strong><span class="s1">LECT 6. </span>NEONATAL SKIN AND RARE DISEASES • </strong>S. Savasta (Cagliari, Italy)</p> <p class="p1"><strong><span class="s1">LECT 7. </span>PREVENTION AND EARLY CARE OF PRESSURE ULCERS IN THE NICU SETTING: A QUALITY IMPROVEMENT PROJECT • </strong>G. Ciprandi (Rome, Italy)</p> <p class="p1"><strong><span class="s1">LECT 8. </span>SEPSIS AND ITS TREATMENT FROM NEWBORNS TO ADULTS • </strong>G. Finco (Cagliari, Italy)</p> <p class="p1"><strong><span class="s1">LECT 9. </span>ARTIFICIAL INTELLIGENCE IN NEONATOLOGY • </strong>K.K. Kope<span class="s2">ć</span>, A. Noto, C. Piras, M. Spada, L. Atzori, V. Fanos (Cagliari, Italy)</p> <p class="p1"><strong><span class="s1">LECT 10. </span>AUTISTIC SPECTRUM DISORDERS IN NICU CANDIDATES • </strong>E. Tsekoura (Athens, Greece)</p> <p class="p1"><strong><span class="s1">LECT 11. RESPIRATORY SYNCYTIAL VIRUS (RSV)</span> INFECTION: NOT ONLY PRETERM INFANTS • </strong>E. Lanfranchi (Urbino, Italy)</p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130208 Fri, 25 Oct 2024 00:00:00 +0200 Selected Lectures of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 https://jpnim.com/index.php/jpnim/article/view/e130206 <p class="p1"><strong><span class="s1">Selected Lectures of the 20<sup>th</sup> International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23<sup>rd</sup>-26<sup>th</sup>, 2024</span></strong></p> <p class="p1"><strong><span class="s1">CHILDREN’S HEALTH: MESSAGES FROM THE FUTURE</span></strong></p> <p class="p1"> </p> <p class="p1"><span class="s1">The Workshop has been organized with the <strong>patronage</strong> of Autonomous Region of Sardinia, City of Cagliari, Azienda Ospedaliera di Cagliari, University of Cagliari, Board of Physicians of the Province of Cagliari, Italian-Albanian Pediatric Society, AMBO (Alleanza per un Ambiente a misura di Bambino: alliance for a child-friendly environment), European Project Better4u, Eropean Project Life Milch, National Confederation of Pediatrics Heads (CONAPP), Italian Federation of Family Pediatricians (FIMP), Italian-Arabian Pediatric Society (IAPS), Italian-Romanian Pediatric Society (IRPS), Norman Group of Neonatal and Pediatric Nephrology, International Academy of Perinatal Medicine, Italian Society of Pediatric Allergology and Immunology (SIAIP), Italian Society of Clinical Biochemistry (SIBioC), Italian Society of Gynecology of Infancy and Adolescence (SIGIA), Italian Society of Neonatology (SIN), Italian Society of Hospital Pediatricians (SIPO), Association SIPO in the World, Italian Society of Pediatric Psichology (S.I.P.Ped.), Romanian Society of Pediatrics, Italian Society for Research on Essential Oils (SIROE), Italian Society of Neonatal Nursing (SIN INF), Union of European Neonatal and Perinatal Societies (UENPS). </span></p> <p class="p1"> </p> <p class="p1"><span class="s1"><strong>LECT 1. NEONATOLOGY FROM THE PAST TO THE FUTURE • </strong></span>G. Buonocore (Siena, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 2. HUMAN BREAST MILK MICROBIOTA AND CHILDREN’S HEALTH • </strong></span>G. Corsello (Palermo, Italy)</p> <p class="p1"><span class="s2"><strong><span class="s1">LECT 3. </span>DEVELOPMENTAL NEUROBIOLOGY: THE EVO</strong></span><span class="s1"><strong>LUTION OF NEONATAL BRAIN • </strong></span>M. Ruggieri (Catania, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 4. FETAL PROGRAMMING OF ADULT DISEASES • </strong></span>G. Faa, M. Fraschini, F. Cau, V. Fanos (Cagliari, Italy; Philadelphia, PA, USA)</p> <p class="p1"><span class="s1"><strong>LECT 5. SKIN MICROBIOTA IN ATOPIC DERMATITIS: IS IT POSSIBLE AN INTERVENTION? • </strong></span>D. Peroni (Pisa, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 6. SKINOMICS: SKIN METABOLOMICS AND MICROBIOMICS • </strong></span>A. Dessì, A. Bosco (Cagliari, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 7. PULMONARY HYPERTENSION IN THE NEWBORN • </strong></span>P.P. Bassareo (Dublin, Ireland )</p> <p class="p1"><span class="s1"><strong>LECT 8. LOOKING FOR A VEIN? THERE IS A LIGHT AT THE END OF THE TUNNEL • </strong></span>A. Lai, C. Lobina (Cagliari, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 9. NEONATAL TRANSPORT BY HELICOPTER • </strong></span>S. Rugolotto (Rovigo, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 10. THE NUTRIENT CYCLE: FROM MATERNAL NUTRITION TO HUMAN MILK COMPOSITION VIA PLACENTA-FETAL EXCHANGES • </strong></span>I. Ten-Doménech, A.C.C. Hodgson, P. Refinetti, J. Kuligowski, S. Rezzi (Valencia, Spain; Lausanne and Monthey, Switzerland)</p> <p class="p1"><span class="s1"><strong>LECT 11. IS IT STILL TIME FOR SUSTAINED INFLATION IN THE DELIVERY ROOM? • </strong></span>G. Lista, F. Castoldi, F. Cavigioli (Milan, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 12. INFECTIONS AND ANTIMICROBIAL USE • </strong></span>A. Charitou (Athens, Greece)</p> <p class="p1"><span class="s1"><strong>LECT 13. NEUROPROTECTIVE STRATEGIES FOR ASPHYXIATED NEWBORNS IN THE EARLY NEONATAL PERIOD: A FOCUS ON BRAIN-ORIENTED INTERVENTIONS • </strong></span>E. Gitto, F. D’Amico, A. Carcione, S. Calabrese (Messina, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 14. METABOLOMICS IN NECROTIZING ENTEROCOLITIS • </strong></span>A. Bosco, A. Dessì (Cagliari, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 15. LEVERAGING PREDICTIVE ANALYTICS FOR MATERNAL IMMUNIZATION • </strong></span>P. Jog, V. Joshi (Pune, Maharashtra, India)</p> <p class="p1"><span class="s1"><strong>LECT 16. RESPIRATORY SYNCYTIAL VIRUS (RSV) PREVENTION: MESSAGES FROM THE PRESENT • </strong></span>L. Folgori, L. Barcellini, G.V. Zuccotti (Milan, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 17. GENETICS AND EPIGENETICS OF THE FUTURE • </strong></span>L. Stuppia (Chieti, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 18. MENINGITIS TODAY • </strong></span>G. Kuli-Lito, R. Petrela, B. Nezaj, B. Gjonaj, D. Shtembari, J. Zdrave, E. Hysenaj, R. Gjini, V. Mano, N. Gjylameti, E. Rustja, D. Cela (Tirana, Albania)</p> <p class="p1"><span class="s1"><strong>LECT 19. BODY DYSMORPHIC DISORDER • </strong></span>F. Velardi (Rome, Italy)</p> <p class="p1"><span class="s1"><strong>LECT 20. DECODING THE MIND: GENETIC INNOVATIONS IN PSYCHIATRIC RESEARCH AND TREATMENT • </strong></span>A. Ciubar<span class="s3">ă (Galați, Romania)</span></p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130206 Thu, 24 Oct 2024 00:00:00 +0200 Selected Lectures of the 3rd Course of Perinatal and Pediatric Cardiology; Cagliari (Italy); October 23, 2024 https://jpnim.com/index.php/jpnim/article/view/e130205 <p class="p1"><strong><span class="s1">Selected Lectures of the 3<sup>rd</sup> Course of Perinatal and Pediatric Cardiology; Cagliari (Italy); October 23, 2024</span></strong></p> <p class="p1"> </p> <p class="p1"><span class="s1">The 3<sup>rd</sup> Course of Perinatal and Pediatric Cardiology is a Satellite Meeting of the 20th International Workshop on Neonatology and Pediatrics, Cagliari (Italy), October 23<sup>rd</sup>-26<sup>th</sup>, 2024.</span></p> <p class="p1"> </p> <p class="p1"><span class="s1"><strong>LECT 1. PRENATAL DIAGNOSIS OF CONGENITAL HEART DISEASES: HOW AND WHERE TO GIVE BIRTH?</strong> • P. Neroni, A. Atzei (Cagliari, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 2. CARDIOVASCULAR HEALTH AND EXERCISE IN CHILDREN WITH CONGENITAL HEART DISEASES</strong> • F. De Luca (Catania, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 3. HEART AND MIND: THE HIDDEN LINK</strong> • G. Concas, E. Esposito, A. Atzei, P. Neroni (Cagliari, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 4. INTERCURRENT PATHOLOGIES, CONGENITAL HEART DISEASES AND CLINICAL MANAGEMENT: WHAT ELSE?</strong> • A. Atzei, G. Concas, C. Trenta, R. Pintus, P. Neroni (Cagliari, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 5. ARTERIAL HYPERTENSION IN THE CHILD</strong> • P.P. Bassareo (Dublin, Ireland)</span></p> <p class="p1"><span class="s1"><strong>LECT 6. CONGENITAL HEART DISEASE: HOW TO MANAGE THE TRANSITION FROM CHILDHOOD TO ADULTHOOD</strong> • M. Chessa, S. Flocco, A. Magon (Milan, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 7. SPORTS CERTIFICATION: DIFFERENCES BETWEEN ITALY AND OTHER COUNTRIES</strong> • R. Solinas (Cagliari, Italy)</span></p> <p class="p1"><span class="s1"><strong>LECT 8. METABOLOMICS AND PEDIATRIC CARDIOLOGY</strong> • R. Pintus (Cagliari, Italy)</span></p> --- Various Authors Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130205 Wed, 23 Oct 2024 00:00:00 +0200 A systematic review and meta-analysis on the safety and efficacy of premedication prior to elective intubation in neonates https://jpnim.com/index.php/jpnim/article/view/e130201 <p class="p1"><strong>Objective: </strong>Endotracheal intubation, as an emergent but also as an elective procedure, can be stressful and painful, causing hypoxemia, bradycardia, acidosis or increased intracranial pressure. We aimed to investigate the safety and efficacy of premedication prior to elective intubation in order to contribute to the development of a more standardized strategy.</p> <p class="p1"><span class="s1"><strong>Method: </strong>A systematic review and meta-analysis was conducted. The PubMed database was searched using the PICO method and keywords according to MeSH terms were used. Only studies with control groups were included (ran­domized controlled trials, prospective observational and case-control studies).</span></p> <p class="p1"><span class="s2"><strong>Results: </strong>Our search procedure yielded 722 potentially eligible studies. Finally, 26 studies were included for qualitative and quantitative analysis. Blood pressure during intubation was found lower for neonates that received premedication compared to controls (SMD = -1.27; 95% CI [-2.59; 0.05]; p &lt; 0.01). Heart rate change was found higher in the control group (SMD = -0.26; 95% CI [-1.07; 0.55]; p = 0.54). Intervention groups were found to have higher odds for bradycardia (OR = 1.13; 95% CI [0.79; 1.62]; p = 0.51), and less odds for desaturation compared to control groups (OR = 0.69; 95% CI [0.33; 1.45]; p = 0.33). The odds for adverse events were found 3 times lower in the intervention group, in relation to controls (OR = 0.71; 95% CI [0.55; 0.73]; p = 0.012). Intubation time for the intervention groups was lower than controls (SMD = -0.59; 95% CI [-1.06; -0.11]; p &lt; 0.02). Intubation attempts were found marginally increased in the intervention group (ROM = 1.10; 95% CI [0.79; 1.53]; p = 0.57). No difference was found regarding mortality rate between groups.</span></p> <p class="p1"><strong>Conclusion: </strong>Most Neonatal Intensive Care Units should consider premedication prior to intubation for vigorously and active term and preterm infants as a safe and efficient procedure that buffers serious physiological responses and assures better procedural conditions.</p> Ilias Chatziioannidis, Georgios N. Katsaras, Abraham Pouliakis, Zoi Arvanitaki, Dimitra Gialamprinou, Georgios Mitsiakos Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130201 Fri, 23 Aug 2024 00:00:00 +0200 Laryngomalacia and failure to thrive – A case report https://jpnim.com/index.php/jpnim/article/view/e130202 <p class="p1"><span class="s1"><strong>Introduction:</strong> Laryngomalacia (LGM) is the most common congenital anomaly of the larynx and the most frequent cause of stridor in the newborn. Even though it can be a source of concern and anxiety to parents, a large majority of cases usually resolve spontaneously within 18 months of life. However, in infants with signs of severity, a multidisciplinary approach and surgical intervention might be necessary. </span></p> <p class="p1"><span class="s1"><strong>Case report:</strong> We report the case of a full-term 7-week-old infant girl, previously hospitalized in the Neonatal Intensive Care Unit and diagnosed with type II LGM (Olney’s classification). She presented to the Paediatric Emergency Department with stridor at rest, vigorous chest wall retractions and poor weight gain (increase of 10 g/day, weight under the 3<sup>rd</sup> percentile). The infant was admitted to monitor respiratory symptoms and investigate her failure to thrive. However, irrespective of feeding modifications, and after exclusion of other causes of failure to thrive, the infant maintained an insufficient weight gain. Additionally, respiratory symptoms remained exuberant and surgical intervention was determined as the optimal treatment. At 3 months old, supraglottoplasty was performed. At 18 months, she has a weight in the 3<sup>rd</sup>-15<sup>th</sup> percentile range (WHO curves) and is clinically asymptomatic.</span></p> <p class="p1"><span class="s1"><strong>Conclusion:</strong> LGM is a remarkably frequent cause of stridor in infants, but only a rare number of cases require other interventions beyond symptomatic measures. In this report, surgical intervention was of paramount importance to ensure normal growth, emphasising the impact of a multidisciplinary approach in such cases. </span></p> Rita Barroca Macedo, Maria Sousa Dias, Luís Salazar, Pedro Alexandre, Catarina Viveiros, Marco Pereira, Jorge Spratley Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130202 Tue, 27 Aug 2024 00:00:00 +0200 Hemodynamics guided care during extracorporeal membrane oxygenation (ECMO): a case report https://jpnim.com/index.php/jpnim/article/view/e130203 <p class="p1">Congenital diaphragmatic hernia (CDH) represents a population of high risk of major cardiopulmonary decompensation. Maintenance of patency of the patent ductus arteriosus (PDA), using intravenous prostaglandin, is a strategy used by some clinicians to decrease the risk of right ventricular dysfunction. A term infant with CDH presented with pulmonary hypertension unresponsive to aggressive hemodynamic support. Within 12 hours of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) initiation, circuit chugging occurred that was refractory to multiple volume boluses. Targeted neonatal echocardiography (TnECHO) revealed a high-volume left-to-right shunt across the PDA, resulting in decreased blood return to the right atrium. Interventions aimed at reducing the left-to-right PDA shunt led to the resolution of circuit chugging. This report highlights the unique challenge of VA-ECMO flow in the setting of a large PDA and the consequences of interventions, increasing PDA diameter or lowering pulmonary vascular resistance, on the magnitude of systemic-pulmonary shunting and systemic blood flow. TnECHO played a vital role in monitoring hemodynamics and guiding ECMO adjustments.</p> Mohamed Al Kanjo, Regan E. Giesinger, Brady Thomas, Amy H. Stanford, Seth Jackson, Adrianne R. Bischoff, Patrick J. McNamara Copyright (c) 2024 © Hygeia Press https://jpnim.com/index.php/jpnim/article/view/e130203 Wed, 28 Aug 2024 00:00:00 +0200