https://jpnim.com/index.php/jpnim <p>The <strong>Journal of Pediatric and Neonatal Individualized Medicine (JPNIM)</strong> is a peer-reviewed interdisciplinary journal which provides a forum on new perspectives in pediatric and neonatal medicine. The aim is to discuss and to bring readers up to date on the latest in research and clinical pediatrics and neonatology. Special emphasis is on developmental origin of health and disease or perinatal programming and on the so-called ‘-omic’ sciences. Systems medicine blazes a revolutionary trail from reductionist to holistic medicine, from descriptive medicine to predictive medicine, from an epidemiological perspective to a personalized approach. The journal will be relevance to clinicians and researchers concerned with personalized care for the newborn and child. Also medical humanities will be considered in a tailored way.</p> <p>Article submission (original research, review papers, invited editorials and clinical cases) will be considered in the following fields: fetal medicine, perinatology, neonatology, pediatrics, developmental programming, psychology and medical humanities.</p> en-US Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) 2281-0692 <p>© Hygeia Press</p> <p> </p> <h3>Copyright and publishing rights</h3> <p>Regarding copyright, before publication, Authors declare that, in consideration of the action of JPNIM in reviewing and editing their submission, they transfer, assign, or otherwise convey all copyright ownership, including any and all rights incidental thereto, exclusively to the JPNIM Publisher (Hygeia Press di Corridori Marinella).</p> <div> <div> <div> <div> <div> <p>Authors have the opportunity to reuse figures, tables and selected text up to 250 words from their article as finally published, providing that full and accurate credit shall be given to publication in JPNIM and that modifications are noted (otherwise no changes may be made).</p> </div> </div> </div> </div> </div> https://jpnim.com/index.php/jpnim/article/view/e150102 <p class="p1"><strong><span class="s1">Selected Abstracts of the 21^st International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 22^nd-25^th, 2025</span></strong></p> <p class="p1"><strong>EVOLUTION AND REVOLUTION IN NEONATOLOGY AND PEDIATRICS</strong></p> <p class="p1"> </p> <p class="p1"><span class="s1">The Workshop has been organized with the <strong>patronage</strong> of the Autonomous Region of Sardinia, City of Cagliari, Azienda Ospedaliera di Cagliari, University of Cagliari, Board of Physicians of the Province of Cagliari, Albanian-Italian Pediatric Society (AIPS), AMBO (<em>Alleanza per un Ambiente a misura di Bambino</em>: alliance for a child-friendly environment), Board of Directors of Italian Pediatrics Schools, European Project Better4u, European Project Life Milch, National Coordination of Heads of Pediatric Departments (CONAPP), Italian Federation of Family Pediatricians (FIMP), Italian-Arabian Pediatric Society (IAPS), Italian-Romanian Pediatric Society (IRPS), Italian-Swedish Cultural Association (ACIS), Norman Group of Neonatal and Pediatric Nephrology, International Academy of Perinatal Medicine (IAPM), Italian Society of Pediatric Allergology and Immunology (SIAIP), Italian Society of Clinical Biochemistry (SIBioC), Italian Society of Gynecology of Infancy and Adolescence (SIGIA), Italian Society of Neonatology (SIN), “SIPO in the World” Association, Italian Society of Pediatric Psychology (S.I.P.Ped.), Italian Society for Research on Essential Oils (SIROE), Italian Society of Neonatal Nursing (SIN INF), “<em>Pediatria Più</em>” Association, Italian Society of Developmental Origins of Health and Disease (SI-DOHaD), Italian Society of Pediatricians (SIMPE).</span></p> <p> </p> <p><strong>ABS 1. PLATELET TRANSFUSIONS IN NEONATES: IMPACT ON COAGULATION AND IMMUNO­LOGICAL EFFECTS</strong> • D. Gialamprinou (Thessaloniki, Greece)</p> <p><strong>ABS 2. PATTERNS AND ASSOCIATED FACTORS OF CONGENITAL ANOMALIES AMONG NEONATES IN 14 YEMENI GOVERNORATES (2021-2023): A CASE-CONTROL STUDY</strong> • H. Al-Atnah (Sana’a, Yemen)</p> <p><strong>ABS 3. INTERNATIONAL STANDARDS FOR TWIN NEWBORN WEIGHT, LENGTH, AND HEAD CIRCUMFERENCE BY GESTATIONAL AGE AND SEX: THE INTERGROWTH-21^ST CROSS-SECTIONAL STUDY</strong> • F. Giuliani, S. Deantoni, S. Gandino, A. Coscia, I. Stura, S.H. Kennedy, A.T. Papageorghiou, E. Bertino, G. Migliaretti, J. Villar for the International Fetal and Newborn Growth Consortium (INTERGROWTH-21^st) (Turin and Moncalieri, Italy; Oxford, UK)</p> <p><strong>ABS 4. IMPACT OF MATERNAL SARS-CoV-2 INFEC­TION ON NEONATAL URINARY METABOLOME: A LONGITUDINAL STUDY OVER THE FIRST MONTH OF LIFE</strong> • D. Gianotti, F. Cannas, N. Zuddas, A. Kindt, F. Cesare Marincola, V. Fanos (Genoa and Cagliari, Italy; Leiden, The Netherlands)</p> <p><strong>ABS 5. ARTIFICIAL INTELLIGENCE IN NEONATOLOGY: WHERE ARE WE NOW?</strong> • K.K. Kopeć (Cagliari, Italy)</p> <p><strong>ABS 6. A TWISTED TIBIA IN A PRETERM NEONATE</strong> • M. Olla, F. Zanco, F.F. Comisi, E. Esposito, C. Spiga, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 7. SCHRÖDINGER’S FETUS</strong> • S. Nasikas, F.F. Comisi (Athens, Greece; Cagliari, Italy)</p> <p><strong>ABS 8. UNEXPLAINED HYPOTONIA IN THE NEW­BORN: A CASE THAT CHALLENGES FIRST IMPRESSIONS</strong> • E. Esposito, F.F. Comisi, M. Loi, P. Beretta, V. Marinelli, F. Lai, V. Fanos, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 9. ACUTE MONOARTHRITIS IN A PEDIATRIC PATIENT: A CASE OF <em>SALMONELLA</em>-INDUCED REACTIVE ARTHRITIS</strong> • L. Saggioro, M. Casarotto, M.R. Ferrara, F. Marino, C. Lorenzetto, E. Madeddu, S. Bellonzi, F. Rigon, L. Calandriello, F. Sansone, E. Fiumana, S. Rugolotto (Rovigo and Padua, Italy)</p> <p><strong>ABS 10. NUTRITIONAL MANAGEMENT OF THE NEW­BORN WITH NECROTIZING ENTEROCOLITIS: A CASE REPORT</strong> • F. Zanco, E. Esposito, F.F. Comisi, M. Melis, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 11. POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME IN PEDIATRIC AGE: A CASE REPORT</strong> • E. Madeddu, M.R. Ferrara, M. Casarotto, F. Marino, L. Saggioro, F. Rigon, S. Bellonzi, C. Lorenzetto, F. Sansone, L. Calandriello, S. Rugolotto (Rovigo, Padua, and Verona, Italy)</p> <p><strong>ABS 12. INFANTILE COLIC AND INTESTINAL INFLAM­MATION</strong> • B.M. Trapani (Paris, France)</p> <p><strong>ABS 13. A STUDY IN CYCLES: CLINICAL CLUES FROM CHILDHOOD VOMITING</strong> • F.F. Comisi, E. Esposito, F. Zanco, M.G. Cuboni, C. Soddu, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 14. WHEN BREATHING FAILS, BLAME THE HEART</strong> • S. Maninchedda, M.G. Cuboni, V. Lagona, P. Neroni, D. Manus, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 15. UNUSUAL LOCALIZATION OF <em>BARTONELLA HENSELAE</em>: SPONDYLODISCITIS IN A FIVE-YEAR-OLD CHILD</strong> • F. Marino, M.R. Ferrara, M. Casarotto, F. Sansone, S. Bellonzi, C. Lorenzetto, F. Rigon, E. Fiumana, L. Saggioro, L. Calandriello, E. Madeddu, S. Rugolotto (Rovigo, Padua, and Verona, Italy)</p> <p><strong>ABS 16. CLAVICLE FRACTURES AT BIRTH: EXPERI­ENCE FROM TWO CASE REPORTS</strong> • E. Esposito, F.F. Comisi, P. Beretta, F. Zanco, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 17. HIDDEN IN PLAIN SIGHT: WHEN HERPES ISN’T THE ANSWER</strong> • F.F. Comisi, E. Esposito, F. Zanco, M.I. Cicalò, M. Pepe, R. Minelli, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 18. SEPSIS-ASSOCIATED ENCEPHALOPATHY IN A SIX-MONTH-OLD INFANT</strong> • L. Calandriello, M. Casarotto, M.R. Ferrara, S. Bellonzi, C. Lorenzetto, F. Marino, F. Rigon, E. Fiumana, E. Madeddu, A. Mussari, L. Saggioro, F. Sansone, S. Rugolotto (Rovigo, Padua, and Verona, Italy)</p> <p><strong>ABS 19. PREVENTING AND FACING OBESITY THROUGH THE BETTER4U EU-FUNDED PROJECT</strong> • M. Mauri, A. Noto, C. Piras, K.K. Kopeć, P. Baire, L. Atzori, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 20. SUBSTANCES THAT MAY INCREASE THE RISK OF PRECOCIOUS PUBERTY IN CHILDREN</strong> • S. Vendemmia, G. Kuli Lito, D. Anca Plesca, M. Vendemmia (Aversa and Naples, Italy; Tirana, Albania; Bucharest, Romania)</p> <p><strong>ABS 21. LOCKED EYE, PAINFUL HEAD: A RARE PEDIATRIC NEUROPATHY</strong> • M. Pepe, M.G. Cuboni, F.F. Comisi, E. Spreafico, V. Santi, M. Gherardini, A. Chabert, T. Foiadelli, S. Savasta (Cagliari and Pavia, Italy)</p> <p><strong>ABS 22. WHEN SINUSITIS TURNS DANGEROUS: A PEDIATRIC CASE OF POTT’S PUFFY TUMOR WITH INTRACRANIAL EXTENSION</strong> • G. Sanna, M. Pepe, D. Murru, B. Percivale, G. Pintori, G. Masia, A.M. Monni, M. Loi, V. Corsi, C. Marcheselli, A. Cualbu (Cagliari and Nuoro, Italy)</p> <p><strong>ABS 23. BOTULISM IN CHILDREN AND ADULTS</strong> • S. Vendemmia, G. Kuli Lito, D. Anca Plesca, B. Al-Zoubi, M. Vendemmia (Aversa and Naples, Italy; Tirana, Albania; Bucharest, Romania; Amman, Jordan)</p> <p><strong>ABS 24. ANISAKIASIS</strong> • S. Vendemmia, G. Kuli Lito, D. Anca Plesca, B. Al-Zoubi, M. Vendemmia (Aversa and Naples, Italy; Tirana, Albania; Bucharest, Romania; Amman, Jordan)</p> <p><strong>ABS 25. MRI BEYOND CT IN PEDIATRIC SPINAL TRAUMA: A CASE REPORT</strong> • M. Pepe, G. Sanna, D. Murru, B. Percivale, G. Pintori, G. Masia, A.M. Monni, M. Loi, V. Corsi, C. Marcheselli, A. Cualbu (Cagliari and Nuoro, Italy)</p> <p><strong>ABS 26. SYSTEMIC LUPUS ERYTHEMATOSUS IN A PEDIATRIC PATIENT: A CASE WITH ONSET COMPLICATED BY CONCOMITANT VISCERAL LEISHMANIASIS</strong> • C. Trenta, C. Giardino, P. Currao, V. Ibba, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 27. A (NOT SO) UNEXPECTED PERINATAL STROKE: WHY EARLY RISK IDENTIFICATION MATTERS</strong> • V. Lagona, M.G. Cuboni, S. Maninchedda, M. Melis, M. Loi, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 28. PERIVIABILITY AND THE CINDERELLA EFFECT</strong> • S. Nasikas, F.F. Comisi (Athens, Greece; Cagliari, Italy)</p> <p><strong>ABS 29. OSTEOMYELITIS OF THE CLAVICLE IN A PEDIATRIC PATIENT: A CASE REPORT</strong> • F. Zara, F. Marino, M.R. Ferrara, M. Casarotto, F. Sansone, S. Bellonzi, C. Lorenzetto, F. Rigon, E. Fiumana, L. Saggioro, L. Calandriello, E. Madeddu, S. Rugolotto (Padua, Rovigo, and Verona, Italy)</p> <p><strong>ABS 30. A COMPLEX CLINICAL CASE ON THE MANAGEMENT OF LATE PRETERM INFANT</strong> • F. Zanco, E. Esposito, F.F. Comisi, A. Atzei, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 31. TRANSIENT ELEVATION OF FECAL CALPROTECTIN IN AN INFANT: CASE REPORT</strong> • G. Trapani (Sanremo, Italy)</p> <p><strong>ABS 32. PD-L1 EXPRESSION IN THE HUMAN PLACENTA AT THE MATERNAL-FETAL INTERFACE PROTECTS FETAL DEVELOPMENT, ESTABLISHING MATERNAL IMMUNO­TOLERANCE</strong> • M. Piras, P. Ziranu, A. Pretta, M. Piludu, F. Cau, G.S. Porcu, G. Faa (Cagliari and San Gavino, Italy; Philadelphia, PA, USA)</p> <p><strong>ABS 33. METABOLOMIC INSIGHTS AND RESEARCH GAPS IN RUGBY: FROM ACUTE RESPONSES TO RECOVERY</strong> • V. Bongiovanni, M. Caria, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 34. WEST NILE AND USUTU VIRUSES</strong> • S. Vendemmia, G. Kuli Lito, D. Anca Plesca, M. Vendemmia (Aversa and Naples, Italy; Tirana, Albania; Bucharest, Romania)</p> <p><strong>ABS 35. SPORTOMICS: BASKETBALL AND VOLLEY­BALL</strong> • M. Caria, V. Bongiovanni, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 36. EXPLORING UNCERTAINTY: LONG-TERM OUT­COMES AND NEUROPLASTICITY AFTER PRE­NATAL BRAIN HEMORRHAGE</strong> • V. Bongiovanni, M. Melis, V. Marinelli, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 37. THE SYNDROME WITH A THOUSAND FACES: A PEDIATRIC PRESENTATION OF SJÖGREN’S SYNDROME</strong> • M. Rossi, S. Campus, V. Ibba, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 38. NEONATAL TRANSPORT FROM THE ISLANDS: A COMPARISON BETWEEN SARDINIA AND THE AZORES</strong> • R. Pirisino, A. Atzei, R. Couto, V. Fanos (Cagliari, Italy; Angra do Heroísmo, Ilha Terceira, Azores, Portugal)</p> <p><strong>ABS 39. ECHOES IN THE CSF: METABOLOMIC MARKERS OF ACUTE IMMUNE NEUROPATHIES</strong> • F.F. Comisi, R. Pintus, E. Esposito, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 40. MATERNAL LIFESTYLES AND ENDOCRINE-DISRUPTING CHEMICALS: SARDINIAN COHORT IN THE EUROPEAN LIFE-MILCH PROJECT</strong> • F. Gola, S. Petza, R. Pintus, S. Angioni, P. Palanza, M.E. Street, A.M. Papini, A. Dessì, V. Fanos (Cagliari, Parma, and Sesto Fiorentino, Italy)</p> <p><strong>ABS 41. PERINATAL INFLAMMATION: A CHALLENGE FOR FETAL NEURODEVELOPMENT</strong> • C. Loddo, R. Pintus, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 42. ASSOCIATION OF ENDOTHELIN-1 AND CYTOKINE LEVELS WITH HYPERFIBRINOLYSIS OF PREGNANT WOMEN WITH PREECLAMPSIA AND THE DEFICITS IN FIBRINOGEN AND EXTRINSIC PATHWAY FACTORS OF THEIR NEONATES</strong> • C.G. Kontovazainitis, D. Gialamprinou, A. Fleva, A. Giannakou, M.E. Bessina, M. Varsami, T. Theodoridis, E. Diamanti, G. Mitsiakos (Thessaloniki, Greece)</p> <p><strong>ABS 43. AMONG NEONATES BORN TO WOMEN WITH PRE­ECLAMPSIA, BRONCHOPULMONARY DYSPLASIA IS ASSOCIATED WITH INTERLEU­KIN 2 LEVELS AT BIRTH, WHILE NEONATAL THROMBOCYTOPENIA IS ASSOCIATED WITH MATERNAL INTERLEUKIN 2 AND ENDOTHE­LIN</strong> • C.G. Kontovazainitis, D. Gialamprinou, A. Fleva, A. Giannakou, M. Varsami, M.E. Bessina, A. Pouliakis, T. Theodoridis, E. Diamanti, G. Mitsiakos (Thessaloniki and Athens, Greece)</p> <p><strong>ABS 44. PEDIATRIC ARTERIAL TORTUOSITY SYN­DROME: CLINICAL AND GENETIC INSIGHTS FROM KOSOVO</strong> • A. Maloku, A. Mustafa, U. Rexha, R. Bejiqi (Prishtina and Gjakova, Republic of Kosovo)</p> <p><strong>ABS 45. IRON-DEFICIENCY ANAEMIA IN PEDIATRIC CONGENITAL HEART DISEASE: A SIX-MONTH CLINICAL EVALUATION</strong> • A. Maloku, R. Bejiqi, A. Gerguri (Prishtina and Gjakova, Republic of Kosovo)</p> <p><strong>ABS 46. SUCCESSFUL MANAGEMENT OF PEDIATRIC PITYRIASIS RUBRA PILARIS WITH ETANERCEPT: A CASE REPORT FROM PRISHTINA</strong> • A. Maloku, A. Gerguri, A. Batalli (Prishtina, Republic of Kosovo)</p> <p><strong>ABS 47. TRUNCUS ARTERIOSUS: MANAGEMENT OF AN UNEXPECTED HEART</strong> • A. Abis, A. Atzei, G. Ottonello, P. Neroni (Cagliari, Italy)</p> <p><strong>ABS 48. PEDIATRIC VOMITING: A CLINICAL CHALLENGE</strong> • A. Barsalini, L. Anedda, E. Erriu, G. Cherchi (Cagliari, Italy)</p> <p><strong>ABS 49. BEYOND THE HEART: A COMPLEX CLINICAL CASE</strong> • E. Esposito, P. Beretta, F.F. Comisi, F. Zanco, P. Neroni, A. Dessì, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 50. OCULAR FISHHOOK INJURY IN A 6-YEAR-OLD PATIENT</strong> • C. Sbaffi, D. Bonsanto, R. Puxeddu, M. D’Atri, G. Cherchi (Cagliari, Italy)</p> <p><strong>ABS 51. LOOK BETTER TO SEE BEYOND: A DIAGNOS­TIC CHALLENGE IN PEDIATRIC CHOROIDAL DETACHMENT</strong> • C. Giardino, A. Corrias, C. Soddu, S. Savasta (Cagliari, Italy)</p> <p><strong>ABS 52. CASE REPORT OF AN EARLY PRETERM NEWBORN WITH PRENATAL DIAGNOSIS OF SHAAF-YANG SINDROME</strong> • A. Lai, D. Rizzo, M. Loi, V. Fanos (Cagliari, Italy)</p> <p><strong>ABS 53. FLOPPY INFANT: MORE THAN JUST WEAKNESS</strong> • M. Rossi, A. Corrias, M. Marica, S. Savasta (Cagliari, Italy)</p> --- Various Authors Copyright (c) 2025 © Hygeia Press 2025-11-30 2025-11-30 15 1 e150102 e150102 10.7363/150102 https://jpnim.com/index.php/jpnim/article/view/e150101 <p class="p1"><strong><span class="s1">Selected Abstracts of the XI National Congress of SIMPEets (Italian Society of Pediatricians, Third Sector Organization, <em>Società Italiana Medici Pediatri, Ente del Terzo Settore</em>); Naples (Italy); November 28-30, 2025</span></strong></p> <p class="p1"> </p> <p class="p1"><span class="s1"><strong>NO ONE LEFT BEHIND. A NEW WAY OF BEING PEDIATRICIANS. GOOD CLINICAL AND SOCIAL PRACTICES <br /></strong></span><span class="s1"><strong>[NESSUNO ESCLUSO. UN NUOVO MODO DI ESSERE PEDIATRI. LE BUONE PRATICHE CLINICHE E SOCIALI]</strong></span></p> <p class="p1"> </p> <p class="p1"><strong>ABS 1. NO ONE EXCLUDED: A NEW WAY OF BEING PEDIATRICIANS </strong><strong>[NESSUNO ESCLUSO: UN NUOVO MODO DI ESSERE PEDIATRI] • </strong>M. Giuliano, G. Mele</p> <p class="p1"><strong>ABS 2. THE ESSENTIAL ROLE OF NUTRITION IN NEURODEVELOPMENT </strong><strong>[ESSENZIALITÀ DELLA NUTRIZIONE PER IL NEUROSVILUPPO] • </strong>G. Trapani</p> <p class="p1"><strong>ABS 3. QUALITY MARKERS OF BOVINE MILK AND NUTRITIONAL WELL-BEING </strong><strong>[MARCATORI DI QUALITÀ DEL LATTE E BENESSERE NUTRIZIONALE] • </strong>L. Cavallarin, S. Cirrincione, M. Giribaldi, C. Lamberti</p> <p class="p1"><strong>ABS 4. INFLUENZA VACCINATION BETWEEN APPRO­PRIATENESS AND COVERAGE: IS THE ROAD STILL LONG? </strong><strong>[LA VACCINAZIONE ANTINFLUENZALE TRA APPROPRIATEZZA E COPERTURE: LA STRADA È ANCORA LUNGA?] • </strong>R. Russo</p> <p class="p1"><strong>ABS 5. KEY DETERMINANTS OF PEDIATRIC HEALTH AND NEURODEVELOPMENT </strong><strong>[I DETERMINANTI CHIAVE PER LA SALUTE PEDIATRICA E IL NEUROSVILUPPO] • </strong>G. Squazzini </p> <p class="p1"><strong>ABS 6. INTERCEPTIVE ORTHODONTICS: WHY THE PEDIATRICIAN PLAYS A KEY ROLE </strong><strong>[ORTODONZIA INTERCETTIVA: PERCHÉ IL PEDIATRA È FONDAMENTALE] • </strong>S. Zizzo, P. Manzo</p> <p class="p1"><strong>ABS 7. INFANTILE HEMANGIOMAS </strong><strong>[GLI EMANGIOMI INFANTILI] • </strong>F. Barbato</p> <p class="p1"><strong>ABS 8. ELECTROCARDIOGRAPHY AT HAND IN THE FAMILY PEDIATRICIAN’S OFFICE </strong><strong>[L’ELETTROCARDIOGRAMMA A PORTATA DI MANO NELL’AMBULATORIO DEL PEDIATRA DI FAMIGLIA] • </strong>F. De Luca, A. Putortì, M. Giuliano</p> <p class="p1"><strong>ABS 9. RARE DISEASES: THE ROLE OF GENETIC TESTING IN DIAGNOSIS AND GENETIC COUNSELING </strong><strong>[MALATTIE RARE: IL RUOLO DEGLI ESAMI GENETICI AI FINI DIAGNOSTICI E DEL COUNSELING GENETICO] • </strong>M. Priolo</p> <p class="p1"><strong>ABS 10. RSV PROPHYLAXIS WITH NIRSEVIMAB IN BIRTH CENTERS OF THE CAMPANIA REGION: RESULTS FROM THE 2024-2025 SEASON </strong><strong>[PROFILASSI ANTI-VRS CON NIRSEVIMAB NEI PUNTI NASCITA DELLA CAMPANIA: I RISULTATI DELLA STAGIONE 2024-2025] • </strong>A. Umbaldo, G. D’Uonno, F. Raimondi</p> <p class="p1"><strong>ABS 11. BIOACTIVE NUTRITIONAL COMPONENTS AND NEURODEVELOPMENTAL PROTECTION FROM ENVIRONMENTAL CONTAMINANTS </strong><strong>[COMPONENTI NUTRIZIONALI BIOATTIVI E PROTEZIONE DEL NEUROSVILUPPO DAI CON­TAMINANTI AMBIENTALI] • </strong>B.M. Trapani</p> <p class="p1"><strong>ABS 12. CARE: EMPATHIC ROBOTICS FOR THERAPY AND MONITORING </strong><strong>[CARE: LA ROBOTICA EMPATICA PER TERAPIA E MONITORAGGIO] • </strong>C. Autorino, M. Staffa</p> --- Various Authors Copyright (c) 2025 © Hygeia Press 2025-11-27 2025-11-27 15 1 e150101 e150101 10.7363/150101 https://jpnim.com/index.php/jpnim/article/view/e150105 <p class="p1"><span class="s1">Artificial intelligence (AI) is used in medicine to assist clinicians in diagnosing and treating patients with various medical conditions. It can have specific benefits for children with special needs, as it can assist in </span>daily activities by enhancing support for these children. The incidence and <span class="s2">prevalence of autism spectrum disorder (ASD) are rapidly increasing. ASD </span><span class="s1">can be associated with other comorbid conditions involving multisystem medical and genetic disorders. AI can help with the early diagnosis and management of ASD and related comorbid conditions. This review aimed to study how AI can be used in patients with ASD and comorbidities.</span></p> <p class="p1"><span class="s1">A narrative review was conducted to find the answer to the study. </span><span class="s3">Electronic </span><span class="s1">PubMed/Medline and Google Scholar databases were searched for peer-reviewed articles. Papers that were not written in the English language were excluded. Results of the study found that, along with providing autistic children the practice of identifying facial expressions, interacting socially, and responding appropriately to social cues, AI can help deal with complex comorbid conditions. AI heavily depends on large amounts of good-quality data, so it faces fundamental technological challenges, such as hallucinations, false results, data privacy, security, and ethical concerns. However, by addressing the challenges and limitations, AI can be a great tool for children with ASD and their families to navigate the associated comorbidities and improve the overall quality of life of these patients. Future research and collaboration of providers with policymakers and community partners can overcome the challenges for AI applications in patients with ASD and associated comorbidities.</span></p> Sandhya J. Kadam Yasamin Pashmineh Azar Swetang J. Shah Copyright (c) 2026 © Hygeia Press 2026-03-03 2026-03-03 15 1 e150105 e150105 10.7363/150105 https://jpnim.com/index.php/jpnim/article/view/e150106 <p class="p1"><strong>ENGLISH TEXT: </strong>The use of low-dose medicinal products, diluted and subjected to standardized succussion treatment or dynamization, has been recognized by the World Health Organization as a component of Traditional, Complementary and Integrative Medicine, and is widespread in more than 100 countries, with over 600 million users. It is based on holistic principles and on a unique production process. This article presents an overview of fundamental research, articulated along two lines: chemical-physical studies – <span class="s1">which, thanks to advanced techniques such as Raman and UV-vis spectroscopy, nuclear magnetic resonance, and differential scanning calorimetry, have highlighted electromagnetic signatures and specific reorganizations of water molecules in dynamized dilutions; and biological studies, conducted in vitro (human cells and microglia) and in vivo (<em>Lemna gibba</em>, frog tadpoles, murine models), which document measurable effects in­dependent of placebo. Some studies hypothesize </span>mechanisms based on nanostructures and possible <span class="s1">electromagnetic interactions. These hypotheses remain controversial and require further in­dependent experimental confirmation. Finally, studies on the use of such medicinal products in developmental age are analyzed, discussing clinical implications, future perspectives, and methodological challenges, and underscoring the importance of rigorous standards to integrate the use of low-dose medicinal products subjected to standardized dynamization treatment into modern healthcare systems. Although not exhaustive, this article offers insights for further investigation and for the optimization of research protocols with a high level of methodological rigor.</span></p> <p class="p1"><strong>ITALIAN TEXT: </strong>L’utilizzo di medicinali a basso dosaggio, diluiti e sottoposti a trattamento di succussione standardizzato o dinamizzazione, è stato riconosciuto dall’Organizzazione Mondiale della Sanità come componente delle Medicine Tradizionali, Complementari e Integrative, ed è diffuso in oltre 100 paesi, con più di 600 milioni di utenti. Si fonda su principi olistici e su un processo unico di produzione. Questo articolo presenta una panoramica della ricerca fondamentale, articolata in <span class="s2">due filoni: studi chimico-fisici – che, grazie a tecniche </span>avanzate come la spettroscopia Raman, UV-vis, la risonanza magnetica nucleare e la calorimetria differenziale a scansione, hanno messo in luce firme elettromagnetiche e riorganizzazioni specifiche delle molecole d’acqua nelle diluizioni dinamizzate; studi biologici, condotti in vitro (cellule umane e microglia) e in vivo (<em>Lemna gibba</em>, girini di rana, modelli murini), che documentano effetti misurabili indipendenti dal placebo. Alcuni studi ipotizzano meccanismi basati su nanostrutture e possibili interazioni elettromagnetiche. Tali ipotesi restano controverse e necessitano di ulteriori conferme sperimentali indipendenti. Infine, si analizzano studi sull’uso di tali medicinali nell’età evolutiva, discutendo implicazioni cliniche, prospettive future e sfide metodologiche, e sottolineando l’importanza di standard rigorosi per integrare l’uso dei medi­cinali a basso dosaggio sottoposti a trattamento di dinamizzazione standardizzato nei sistemi sanitari moderni. Sebbene non esaustivo, questo articolo offre spunti per ulteriori approfondimenti e per l’ottimizzazione di protocolli di ricerca ad alto rigore metodologico.</p> Gianfranco Trapani Marco Lauro Copyright (c) 2026 © Hygeia Press 2026-03-06 2026-03-06 15 1 e150106 e150106 10.7363/150106 https://jpnim.com/index.php/jpnim/article/view/e150104 <p class="p1">McCune-Albright syndrome (MAS) is defined by the triad of <em>café-au-lait </em>macules, endocrinopathies, and polyostatic fibrous dysplasia (FD) of the bone. It results from somatic <em>GNAS</em> mutations leading to mosaic Gαs activation. FD can result in bone deformities, fractures, and cranial nerve compression, including optic neuropathy. Optic nerve compression by FD may lead to visual disturbances or even blindness.</p> <p class="p1">We report a 13-year-old boy with MAS and left eye visual impairment due to optic nerve compression by FD.</p> <p class="p1">Endoscopic transnasal optic nerve decompression of the optic nerve was performed. Postoperatively, the patient exhibited slight visual improvement, though delayed intervention may have limited recovery.</p> <p class="p1">The case report highlights endoscopic decompression as a safe and ef­fective approach for FD-related optic neuropathy, though optimal timing remains debated. Prophylactic intervention in high-risk cases warrants further investigation to prevent irreversible vision loss.</p> Mazin Mahmoud Fawzi Muaid Ismaiel Aziz Baban Basil Mohammednatheer Saeed Faehaa A. Al-Mashhadane Copyright (c) 2026 © Hygeia Press 2026-02-25 2026-02-25 15 1 e150104 e150104 10.7363/150104