DILI (drug induced liver injury) in a 9-month-old infant: a rare case of phenobarbital-induced hepatotoxicity
Vol. 2 No. 1 (2013), Articles
Vol. 2 No. 1 (2013)

DILI (drug induced liver injury) in a 9-month-old infant: a rare case of phenobarbital-induced hepatotoxicity

Articles
https://doi.org/10.7363/020114
Published 2013-04-04
Anna Paola Pinna
Department of Pediatrics and Clinical Medicine, AOU and University of Cagliari
Gabriella Locci
Department of Pathology, AOU and University of Cagliari
Maria Furno
Department of Pediatrics and Clinical Medicine, AOU and University of Cagliari
Daniela Fanni
Department of Pathology, AOU and University of Cagliari
Gavino Faa
Department of Pathology, AOU and University of Cagliari
Anna Maria Nurchi
Department of Pediatrics and Clinical Medicine, AOU and University of Cagliari
JPNIM Vol. 2 N. 1 - Cover
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Keywords

DILI
infant
phenobarbital
CYP3A4

How to Cite

Pinna, A. P., Locci, G., Furno, M., Fanni, D., Faa, G., & Nurchi, A. M. (2013). DILI (drug induced liver injury) in a 9-month-old infant: a rare case of phenobarbital-induced hepatotoxicity. Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), 2(1), 93-95. https://doi.org/10.7363/020114
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Abstract

Phenobarbital is one of the most commonly prescribed antiepileptic drugs in childhood, but it can rarely cause serious adverse effects, such as hepatotoxicity that includes a broad clinical spectrum (from isolate hypertransaminasemia to acute liver failure). We describe a case of DILI in a 9-month-old infant caused by chronic therapy with phenobarbital.

https://doi.org/10.7363/020114
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