Introduction: Stevens-Johnson Syndrome (SJS) is a rare mucocutaneous disease whose incidence increases with age and about 20% of cases occur in children and adolescents. Mortality reaches 5%.
Case description: We present a male adolescent, 11 years old, admitted due to oral mucosa erosions, lips edema and erythema, enanthema, cutaneous target lesions and edemaciate, erythematous and exudative glans, treated with non-steroidal anti-inflammatory drugs one day before the onset of cutaneous symptoms. The diagnostic tests didn’t show alterations and microbiological tests and serologies were negative. The patient was admitted to the Pediatrics Department with diagnosis of SJS. He was hospitalized for 10 days with intravenous analgesia, mucositis solution and topical emollient, hydric and nutritional reinforcement. He exhibited successive improvement of lesions with complete resolution after 2 weeks.
Conclusions: The diagnosis of SJS is clinical, with special emphasis to the use of drugs or the presence of previous infection. Its recognition is important so that clinical intervention can occur as early as possible, decreasing the likelihood of complications and death.