Placental growth factor and placental perfusion
Vol. 3 No. 2 (2014), Articles
Vol. 3 No. 2 (2014)

Placental growth factor and placental perfusion

Articles
https://doi.org/10.7363/030248
Published 2014-10-21
Sara Francesca Deiana
Department of Obstetrics and Gynecology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Ileana Atzeni
Department of Obstetrics and Gynecology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Alessandra Meloni
Department of Obstetrics and Gynecology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Silvia Soddu
Department of Pathology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Giuseppina Parodo
Department of Pathology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Melania Puddu
Neonatal Intensive Care Unit, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Erica Vannelli
Neonatal Intensive Care Unit, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Alessandra Atzei
Neonatal Intensive Care Unit, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Gavino Faa
Department of Pathology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Vassilios Fanos
Neonatal Intensive Care Unit, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Gian Benedetto Melis
Department of Obstetrics and Gynecology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
Anna Maria Paoletti
Department of Obstetrics and Gynecology, University of Cagliari, Azienda Ospedaliero Universitaria, Cagliari, Italy
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Keywords

placental growth factor
placental function
preterm delivery
placental perfusion
neonatal outcomes

How to Cite

Deiana, S. F., Atzeni, I., Meloni, A., Soddu, S., Parodo, G., Puddu, M., Vannelli, E., Atzei, A., Faa, G., Fanos, V., Melis, G. B., & Paoletti, A. M. (2014). Placental growth factor and placental perfusion. Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), 3(2), e030248. https://doi.org/10.7363/030248
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Abstract

Placental Growth Factor (PlGF) is a very important angiogenic protein secreted by the placenta, necessary for the proper functioning of the endothelial cells during pregnancy. In normal pregnancies, PlGF plasma circulating levels increase up to the 32nd week of pregnancy, and then decrease until the end of pregnancy. Low PlGF plasma levels are a marker of preeclampsia and of placental function deficiency. The aim of our study was to evaluate whether a deficiency of placenta function, diagnosed through the PlGF assay, could be a cause of preterm delivery without known causes. The PlGF levels were measured in plasma samples collected by 250 pregnant women (20-35 weeks of pregnancy). In our study, PlGF levels were significantly lower than cut off values in all women with preterm delivery without known causes.

 

Proceedings of the International Course on Perinatal Pathology (part of the 10th International Workshop on Neonatology · October 22nd-25th, 2014) · Cagliari (Italy) · October 25th, 2014 · The role of the clinical pathological dialogue in problem solving

Guest Editors: Gavino Faa, Vassilios Fanos, Peter Van Eyken

https://doi.org/10.7363/030248
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