TY - JOUR AU - Nemolato, Sonia AU - Sanna, Alice AU - Gerosa, Clara AU - Fanni, Daniela AU - Palmas, Giuliana AU - Puddu, Melania AU - Loddo, Cristina AU - Fanni, Claudia AU - Van Eyken, Peter AU - Faa, Gavino PY - 2013/02/16 Y2 - 2024/03/29 TI - Peri and intraglomerular haematoxylinophilic deposits in a newborn: question JF - Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) JA - J Pediatr Neonat Individual Med VL - 2 IS - 1 SE - DO - 10.7363/020109 UR - https://jpnim.com/index.php/jpnim/article/view/020109 SP - 96-97 AB - <p>A female preterm infant, weighing 2,480 g, was born in a first level Hospital, with caesarean section performed for acute fetal distress. The mother, a 34 years old woman, had a previous healthy child. At birth the general conditions were good. At cardiological examination a patent ductus arteriosus was diagnosed. Laboratory values were within normal range. The newborn was discharged after 11 days, in good general conditions and with spontaneous feeding.</p> <p>During a planned cardiologic follow-up control at day 50, cardiac ultrasounds revealed an increase of volume of left atrium and ventriculus, which appears severely hypokinetic. The baby was urgently transferred in a NICU, where she died after 12 hours for heart insufficiency.</p><p>At autopsy, deposition of amorphous material, mainly stained by haematoxylin, in periglomerular location was found in the kidney.</p><p>1. What is your morphological diagnosis?</p> <p>2. Which complementary investigations do you suggest?</p> <p>3. Could be important the examination of large and medium-sized arteries in the heart?</p> ER -