TY - JOUR AU - Katsaras, Georgios N. AU - Gialamprinou, Dimitra AU - Chatziioannidis, Ilias AU - Karagianni, Paraskevi AU - Mitsiakos, Georgios PY - 2022/10/12 Y2 - 2024/03/19 TI - Coagulation factor XIII deficiency – Report of a newborn F13A1 Val34Leu polymorphism carrier JF - Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) JA - J Pediatr Neonat Individual Med VL - 11 IS - 2 SE - DO - 10.7363/110238 UR - https://jpnim.com/index.php/jpnim/article/view/e110238 SP - e110238 AB - <p class="p1">Coagulation factor XIII deficiency (FXIIID) is a rare inherited autosomal recessive bleeding disorder. FXIIID is the only coagulation factor deficiency that has been associated with pregnancy loss. Regarding neonates, prolonged umbilical cord bleeding and intracranial hemorrhage, a life-threatening condition in the neonatal period, have been reported in cases with inherited FXIIID. In this report, we present a case of a newborn of a homozygous <em>F13A1</em> Val34Leu variant mother, while reviewing the current literature.</p> ER -