Adrenal stem cell niches are located between adrenal and renal capsules
Vol. 5 No. 2 (2016), Articles
Vol. 5 No. 2 (2016)

Adrenal stem cell niches are located between adrenal and renal capsules

Articles
https://doi.org/10.7363/050214
Published 2016-08-10
Eleonora Obinu
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Giorgia Locci
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Clara Gerosa
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Vassilios Fanos
Department of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, Italy
Laura Vinci
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Gavino Faa
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Rossano Ambu
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
Cristina Loddo
Department of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, Italy
Elisabetta Coni
Department of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, Italy
Marco Angiolucci
Department of Surgical Sciences, Section of Obstetrics and Gynecology, University of Cagliari, Cagliari, Italy
Claudia Fanni
Department of Surgical Sciences, NICU, Neonatal Pathology, Puericulture Institute and Neonatal Section, University of Cagliari, Cagliari, Italy
Daniela Fanni
Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, Italy
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Keywords

stem/progenitor cells
adrenal glands
adrenal gland stem cell niches
adrenal gland capsule
adrenal gland morphogenesis
adrenal gland development

How to Cite

Obinu, E., Locci, G., Gerosa, C., Fanos, V., Vinci, L., Faa, G., Ambu, R., Loddo, C., Coni, E., Angiolucci, M., Fanni, C., & Fanni, D. (2016). Adrenal stem cell niches are located between adrenal and renal capsules. Journal of Pediatric and Neonatal Individualized Medicine (JPNIM), 5(2), e050214. https://doi.org/10.7363/050214
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Abstract

The human adrenal glands arise around the 4th week of gestation and during the intrauterine life produce many substances that are responsible for the maintenance of fetal homeostasis and organ maturation. Stem cell niches represent the microenvironment suitable for life and replication of adrenal stem cells.
Adrenal gland stem cells have the capacity to self-renew and generate functional differentiated daughter cells that replenish lost cells. Morphologically the adrenal stem cells appeared as small, polymorphic cells, closed together, with basophilic nucleus, located between adrenal and renal capsules. This study was mainly based on a morphological and immunohistochemical approach, particularly on characterization and localization of the multiple stem/progenitor cells that contribute to the development of the human adrenal gland.

Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future
Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordano

https://doi.org/10.7363/050214
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